Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187182 | 1.00 | KMT2A (0.58) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL15187254 | 1.00 | KMT2A (0.58) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL5967892 | 0.98 | KMT2A (0.61) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL15187344 | 0.98 | KMT2A (0.61) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL15187197 | 0.98 | KMT2A (0.61) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL19861424 | 0.94 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL29757428 | 0.91 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL11530689 | 0.91 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL19710826 | 0.87 | KMT2A (0.62) | KMT2AMEN1ALDH1A1L3MBTL1ATM | |
| SCHEMBL3082205 | 0.87 | KMT2A (0.62) | KMT2AMEN1ALDH1A1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273802-A1 | NEW PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTI-PROLIFERATIVE PROPERTIES, AND THEIR BIOLOGICAL USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIGUE (C.N.R.S.) | 2010-10-28 | — | — | US | claimed |
| US-20090030019-A1 | PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTI-PROLIFERATIVE PROPERTIES, AND THEIR BIOLOGICAL USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIGUE (C.N.R.S.) | 2009-01-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273802-A1 | NEW PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTI-PROLIFERATIVE PROPERTIES, AND THEIR BIOLOGICAL USES | PNP, TYMP, DPYD | KMT2A 2565/4885MEN1 4577/4885ALDH1A1 548/4885 |
| US-20090030019-A1 | PURINE DERIVATIVES HAVING, IN PARTICULAR, ANTI-PROLIFERATIVE PROPERTIES, AND THEIR BIOLOGICAL USES | PNP, TYMP, NUDT1 | KMT2A 2144/4885MEN1 4484/4885ALDH1A1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.