2-Picolinic Acid

2-Picolinic Acid

SCHEMBL30822980

O=C(O)c1ccccn1.c1ccc2c(c1)OCO2

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
L3MBTL1 Q9Y468 3/20 0.69
NAPRT Q6XQN6 1/20 0.69
P4HTM Q9NXG6 1/20 0.69
NPC1 O15118 9/20 0.58
RAB9A P51151 9/20 0.58
PKM P14618 5/20 0.55
KDM4E B2RXH2 4/20 0.55
MAPT P10636 3/20 0.55
MAPK1 P28482 2/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
PLIN1 O60240 1/20 0.55
PLIN5 Q00G26 1/20 0.55
ABHD5 Q8WTS1 1/20 0.55
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 6/20 0.51
GAA P10253 1/20 0.51
MITF O75030 1/20 0.51
TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Picolinic Acid SCHEMBL28737810 0.83 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL674837 0.83 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL29368665 0.83
2-Picolinic Acid SCHEMBL36055 0.83
2-Picolinic Acid SCHEMBL7457912 0.83 LMNA (1.00) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL890376 0.81 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL1469 0.81 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL20721125 0.81 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL22835776 0.81 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMNPC1
2-Picolinic Acid SCHEMBL12537807 0.81 LMNA (0.95) LMNAL3MBTL1NAPRTP4HTMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790389-B1 4-AMINO-6-(1,3-BENZODIOXOLE)PICOLINATES AND THEIR USE AS HERBICIDES CORTEVA AGRISCIENCE LLC (US) 2024-02-28 EP disclosed