Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177861 | 1.00 | LMNA (0.41) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21177841 | 1.00 | LMNA (0.41) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21187288 | 1.00 | LMNA (0.41) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21177844 | 1.00 | LMNA (0.41) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL30817828 | 0.95 | PRKDC (0.38) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21177843 | 0.95 | PRKDC (0.38) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21177846 | 0.95 | PRKDC (0.38) | LMNAGAAPIK3CDPIK3R1CYP46A1 | |
| SCHEMBL21179453 | 0.91 | ERBB2 (0.38) | PRKDCERBB2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL21179454 | 0.91 | ERBB2 (0.38) | PRKDCERBB2BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL21178261 | 0.90 | ERBB2 (0.40) | CYP46A1MAPTKDM4EPRKDCGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757876-B | DNA-PK inhibitors | 沃泰克斯药物股份有限公司 | 2024-03-22 | — | — | CN | disclosed |