Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27151963 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL16761769 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL30380295 | 0.83 | GAA (0.47) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL14207376 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL4733393 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL29076894 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL23884915 | 0.80 | NQO2 (0.47) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL4770167 | 0.76 | GABRP (0.65) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29788969 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL9069520 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024041440-A1 | TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-02-29 | — | — | WO | disclosed |