Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318711 | 1.00 | HRH3 (0.47) | HRH3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12531314 | 0.98 | HRH3 (0.49) | HRH3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13940645 | 0.88 | CHKA (0.45) | HRH3ALDH1A1KDM4EATML3MBTL1 | |
| SCHEMBL27110665 | 0.81 | KDM4E (0.46) | HRH3ALDH1A1KDM4EL3MBTL1MAPT | |
| SCHEMBL30218433 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1KDM4C | |
| SCHEMBL21043977 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EL3MBTL1KDM4C | |
| SCHEMBL27318757 | 0.79 | ALDH1A1 (0.43) | HRH3ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL15726764 | 0.78 | KDM4C (0.43) | HRH3ATML3MBTL1HTR3ACHRNB2 | |
| SCHEMBL27319266 | 0.75 | HRH3 (0.44) | HRH3ALDH1A1KDM4EATMHTT | |
| SCHEMBL30824512 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | HRH3 4094/4885ALDH1A1 3122/4885KDM4E 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.