Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22217 | 1.00 | KCNQ3 (0.55) | KCNQ3KCNQ2CTNNB1TCF7L2HTT | |
| SCHEMBL30824694 | 0.91 | CTNNB1 (0.46) | KCNQ3KCNQ2CTNNB1TCF7L2HTT | |
| SCHEMBL20540 | 0.91 | CTNNB1 (0.46) | KCNQ3KCNQ2CTNNB1TCF7L2HTT | |
| SCHEMBL30824684 | 0.90 | MMP13 (0.47) | KCNQ3KCNQ2TP53MAPTMMP13 | |
| SCHEMBL20473 | 0.90 | MMP13 (0.47) | KCNQ3KCNQ2TP53MAPTMMP13 | |
| SCHEMBL21737 | 0.89 | KCNQ3 (0.62) | KCNQ3KCNQ2HTTSMN1; SMN2TP53 | |
| SCHEMBL30795749 | 0.89 | KCNQ3 (0.62) | KCNQ3KCNQ2HTTSMN1; SMN2TP53 | |
| SCHEMBL22343 | 0.85 | L3MBTL1 (0.48) | KCNQ3KCNQ2CTNNB1TCF7L2HTT | |
| SCHEMBL30795753 | 0.85 | L3MBTL1 (0.48) | KCNQ3KCNQ2CTNNB1TCF7L2HTT | |
| SCHEMBL23080 | 0.85 | KCNQ3 (0.58) | KCNQ3KCNQ2HTTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |