Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 3/20 | 0.39 |
| ▸ | RAF1 | P04049 | 9/20 | 0.38 |
| ▸ | BRAF | P15056 | 8/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127971 | 1.00 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2133126 | 0.94 | KDM4E (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL30794972 | 0.94 | KDM4E (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2129392 | 0.94 | KDM4E (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2134391 | 0.91 | RAB9A (0.43) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2129040 | 0.91 | RAB9A (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2130664 | 0.90 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL30795329 | 0.90 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2131119 | 0.90 | ALDH1A1 (0.51) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2130364 | 0.90 | RAB9A (0.42) | ALDH1A1GAAHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |