Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.49 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | GPR4 | P46093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27390612 | 1.00 | RXFP1 (0.52) | RXFP1EPHX2SQORTERTCHRM2 | |
| SCHEMBL2157285 | 0.85 | KDM4E (0.55) | RXFP1EPHX2SQORCHRM2CHRM4 | |
| SCHEMBL30811991 | 0.82 | GPR119 (0.44) | KMT2A | |
| SCHEMBL2165368 | 0.81 | SQOR (0.55) | RXFP1EPHX2SQORCHRM2CHRM4 | |
| SCHEMBL31269095 | 0.81 | RXFP1 (0.45) | RXFP1EPHX2SQORCHRM2CHRM4 | |
| SCHEMBL31614313 | 0.81 | EPHX2 (0.54) | RXFP1EPHX2TERTCHRM2CHRM4 | |
| SCHEMBL1730771 | 0.80 | HRH2 (0.58) | EPHX2SQORDRD2DRD3ALDH1A1 | |
| SCHEMBL16676642 | 0.80 | RXFP1 (0.61) | RXFP1EPHX2CHRM2CHRM4CHRM1 | |
| SCHEMBL30812113 | 0.78 | EPHX2 (0.60) | RXFP1EPHX2CHRM2CHRM4CHRM1 | |
| SCHEMBL4151813 | 0.78 | SQOR (0.54) | RXFP1EPHX2SQORCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054955-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |