Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226259 | 0.86 | CHRM4 (0.37) | CHRM4EPHX2MGLLCHRM2CHRM1 | |
| SCHEMBL30825164 | 0.86 | CHRM4 (0.37) | CHRM4EPHX2MGLLCHRM2CHRM1 | |
| SCHEMBL29226246 | 0.81 | CHRM4 (0.39) | CHRM4EPHX2MGLLCHRM2CHRM1 | |
| SCHEMBL30900290 | 0.81 | CHRM4 (0.39) | CHRM4EPHX2MGLLCHRM2CHRM1 | |
| SCHEMBL29226321 | 0.79 | NR1H2 (0.35) | CHRM4EPHX2MGLLCHRM2CHRM1 | |
| SCHEMBL29226215 | 0.73 | NR1H2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL29226658 | 0.73 | CHRM4 (0.37) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30900418 | 0.73 | CHRM4 (0.37) | CHRM4CHRM2CHRM1CHRM3CHRM5 | |
| SCHEMBL30900288 | 0.72 | MEN1 (0.41) | MAPTSMN1; SMN2 | |
| SCHEMBL29226248 | 0.72 | MEN1 (0.41) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051717-A1 | COMPOUND AS PLK1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-03-14 | — | — | WO | disclosed |