Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651687 | 0.75 | IDO1 (0.49) | IDO1NOTUMCLK4GABRG2GABRB3 | |
| SCHEMBL30311721 | 0.74 | ALDH1A1 (0.49) | IDO1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22053004 | 0.74 | ALDH1A1 (0.49) | IDO1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3754960 | 0.74 | ENPP2 (0.50) | — | |
| SCHEMBL4333689 | 0.74 | IDO1 (0.46) | IDO1PIN1XDH | |
| SCHEMBL4345238 | 0.74 | IDO1 (0.50) | IDO1NOTUMCLK4GABRG2GABRB3 | |
| SCHEMBL12127268 | 0.74 | IDO1 (0.50) | IDO1NOTUMPIN1 | |
| SCHEMBL5784940 | 0.73 | CLK4 (0.49) | IDO1NOTUMCLK4GABRG2GABRB3 | |
| SCHEMBL2052675 | 0.73 | CLK4 (0.57) | IDO1CLK4MAOBPIN1XDH | |
| SCHEMBL2154026 | 0.73 | CLK4 (0.65) | IDO1NOTUMCLK4GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |