Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436510 | 0.85 | PDE10A (0.51) | PDE10AGSRGSK3BPGRFEN1 | |
| SCHEMBL27250770 | 0.84 | PDE10A (0.44) | PDE10AGSRGSK3BPGRFEN1 | |
| SCHEMBL27446451 | 0.82 | PDE10A (0.40) | PDE10AGSRGSK3BPGRFEN1 | |
| SCHEMBL30825851 | 0.82 | USP14 (0.42) | PDE10AGSK3BALDH1A1MAPTHSD17B10 | |
| SCHEMBL27252120 | 0.82 | USP14 (0.42) | PDE10AGSK3BALDH1A1MAPTHSD17B10 | |
| SCHEMBL11437297 | 0.81 | MAT2A (0.54) | PDE10AGSRGSK3BCYP3A4ALOX12 | |
| SCHEMBL8253815 | 0.81 | PDE10A (0.51) | PDE10AGSK3BPGRALDH1A1FEN1 | |
| SCHEMBL24405905 | 0.79 | PDE10A (0.42) | PDE10AGSK3BPGRFEN1MAPK1 | |
| SCHEMBL11436450 | 0.76 | PDE10A (0.51) | PDE10APGRALDH1A1GAAFEN1 | |
| SCHEMBL3515107 | 0.76 | FEN1 (0.53) | PDE10AALDH1A1HSD17B10FEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590396-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062089-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |