SCHEMBL30826326

SCHEMBL30826326

FC(F)(F)Oc1ccc(Cn2c(Br)ccc2Br)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51
CHRM5 P08912 1/20 0.44
TEAD1 P28347 2/20 0.44
FEN1 P39748 1/20 0.41
TYMS P04818 1/20 0.41
HTR2C P28335 1/20 0.41
GRM2 Q14416 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
BACE1 P56817 1/20 0.41
HCRTR1 O43613 5/20 0.40
HCRTR2 O43614 5/20 0.40
DRD4 P21917 3/20 0.40
DRD2 P14416 2/20 0.40
DRD3 P35462 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15242959 0.76 ALDH1A1 (0.49) ALDH1A1TSHRCHRM5TEAD1HTR2C
SCHEMBL3604297 0.76 ALDH1A1 (0.46) ALDH1A1TSHRCHRM5TEAD1HTR2C
SCHEMBL9977495 0.73 MEN1 (0.47) ALDH1A1TSHRCHRM5FEN1GRM2
Ammonia Solution, Strong SCHEMBL25380785 0.72 TSHR (0.56) ALDH1A1TSHRBCHEACHE
SCHEMBL1008825 0.72 ALDH1A1 (0.51) ALDH1A1TSHRCHRM5BCHEACHE
SCHEMBL104233 0.72 ALDH1A1 (0.47) ALDH1A1TSHRCHRM5BCHEACHE
SCHEMBL11100815 0.72 CHRM5 (0.56) ALDH1A1TSHRCHRM5HTR2CGRM2
SCHEMBL2092054 0.72 SLC6A4 (0.56) ALDH1A1TSHRCHRM5BCHEACHE
SCHEMBL18097766 0.71 TSHR (0.55) ALDH1A1TSHRCHRM5TEAD1
SCHEMBL15242981 0.71 ALDH1A1 (0.44) ALDH1A1TSHRCHRM5TEAD1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700457-A Electrochromic compound, preparation method and application 北京大学深圳研究生院 2024-03-15 CN disclosed