Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915171 | 1.00 | LMNA (0.41) | LMNAPOLBKDM4EMAPTROCK2 | |
| SCHEMBL20783225 | 0.85 | LMNA (0.41) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL22200884 | 0.85 | LMNA (0.41) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL30674498 | 0.84 | CA1 (0.34) | LMNAPOLBKDM4EROCK2CA1 | |
| SCHEMBL26915195 | 0.84 | CA1 (0.34) | LMNAPOLBKDM4EROCK2CA1 | |
| SCHEMBL27189820 | 0.84 | LMNA (0.42) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL7664370 | 0.79 | LMNA (0.49) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL24728325 | 0.79 | LMNA (0.42) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL31689123 | 0.79 | LMNA (0.41) | LMNAPOLBKDM4EMAPTCA1 | |
| SCHEMBL26470796 | 0.77 | KDM4E (0.38) | LMNAPOLBKDM4EMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349372-A1 | ANTIBODY DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |