Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200884 | 0.91 | LMNA (0.41) | KDM4ELMNAPOLBMAPTHDAC1 | |
| SCHEMBL20783225 | 0.91 | LMNA (0.41) | KDM4ELMNAPOLBMAPTHDAC1 | |
| SCHEMBL26470798 | 0.90 | RECQL (0.35) | KDM4ELMNAPOLBMAPTPDE10A | |
| SCHEMBL26471057 | 0.89 | KDM4E (0.34) | KDM4ELMNAPOLBMAPTHDAC1 | |
| SCHEMBL26470320 | 0.86 | CYP11B2 (0.42) | KDM4ELMNAPOLBMAPT | |
| SCHEMBL26470794 | 0.86 | KDM4E (0.33) | KDM4ELMNAPOLBMAPTHDAC1 | |
| SCHEMBL26471064 | 0.83 | KDM4E (0.36) | KDM4ELMNAPOLBMAPTPDE10A | |
| SCHEMBL26623065 | 0.82 | HDAC1 (0.36) | KDM4ELMNAHDAC1HDAC6CA1 | |
| SCHEMBL26623089 | 0.81 | HDAC1 (0.35) | KDM4ELMNAMAPTHDAC1HDAC6 | |
| SCHEMBL31689030 | 0.81 | LMNA (0.46) | KDM4ELMNAPOLBMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072143-A1 | CAMPTOTHECIN DERIVATIVE INTERMEDIATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海弼领生物技术有限公司 | 2023-05-04 | — | — | WO | disclosed |