Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.41 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29310766 | 1.00 | TNF (0.47) | TNFPIN1FGFR4MAPTMEN1 | |
| SCHEMBL30079650 | 0.78 | MAPT (0.60) | PIN1FGFR4MAPTMEN1CYP1A2 | |
| SCHEMBL23927084 | 0.78 | MAPT (0.60) | PIN1FGFR4MAPTMEN1CYP1A2 | |
| SCHEMBL718271 | 0.78 | MAPT (0.51) | PIN1FGFR4MAPTMEN1CYP1A2 | |
| SCHEMBL10810171 | 0.77 | GSK3B (0.58) | PIN1MAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL17475834 | 0.77 | FGFR4 (0.44) | PIN1FGFR4MAPTMEN1CYP1A2 | |
| SCHEMBL30827642 | 0.76 | TNF (0.52) | TNFKMT2APIK3CANPC1RAB9A | |
| SCHEMBL27252315 | 0.76 | TNF (0.52) | TNFKMT2APIK3CANPC1RAB9A | |
| SCHEMBL31743939 | 0.76 | MEN1 (0.48) | PIN1MAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL12705359 | 0.75 | FGFR4 (0.52) | PIN1FGFR4MAPTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590397-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062090-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |