Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.71 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828435 | 0.83 | CRBN (1.00) | DDB1CRBNMAPTADRA2C | |
| Hydrochloric Acid SCHEMBL30828456 | 0.81 | CRBN (0.97) | DDB1CRBNMAPTADRA2C | |
| SCHEMBL5182235 | 0.81 | DDB1 (0.47) | DDB1CRBNMAPTKDM4EGAA | |
| SCHEMBL8076294 | 0.81 | DDB1 (0.47) | DDB1CRBNMAPTKDM4EGAA | |
| SCHEMBL1788429 | 0.81 | MEN1 (0.58) | DDB1CRBNMAPTKDM4EGAA | |
| SCHEMBL746783 | 0.79 | CRBN (0.66) | DDB1CRBNMAPTKDM4EGAA | |
| SCHEMBL10814936 | 0.78 | MAPT (0.60) | DDB1CRBNMAPTMEN1KMT2A | |
| SCHEMBL4399681 | 0.78 | F10 (0.56) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31439105 | 0.77 | CRBN (0.63) | DDB1CRBNMAPTKDM4EGAA | |
| SCHEMBL8104104 | 0.77 | CRBN (0.67) | DDB1CRBNMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003094854-A2 | SUCCINOYL AMINOPYRAZOLES AND RELATED COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003064396-A1 | HYDROXYALKANOYL AMINOPYRAZOLES AND RELATED COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2003-08-07 | — | — | WO | disclosed |