SCHEMBL30828488

SCHEMBL30828488

O=C(NC1CCCCC1)c1c2ccccc2nn1-c1cccnc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.49
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
POLB P06746 3/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
HTT P42858 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
GAA P10253 1/20 0.44
LMNA P02545 3/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 2/20 0.43
GLA P06280 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
WNT1 P04628 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29179998 1.00 CNR1 (0.49) CNR1ALDH1A1SMN1; SMN2POLBKMT2A
SCHEMBL30636863 0.82 RAB9A (0.53) CNR1ALDH1A1SMN1; SMN2POLBKMT2A
SCHEMBL31457212 0.77 CHEK1 (0.53) ALDH1A1HTTGAADYRK1A
SCHEMBL16568906 0.77 CNR1 (0.48) CNR1ALDH1A1SMN1; SMN2POLBKMT2A
SCHEMBL29427429 0.77 CNR1 (0.48) CNR1ALDH1A1SMN1; SMN2POLBKMT2A
SCHEMBL30828481 0.76 CCNA2 (0.44) HTTKDM4EDYRK1A
SCHEMBL24405650 0.74 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2POLBKMT2AMEN1
SCHEMBL17688532 0.73 CNR1 (0.41) CNR1ALDH1A1KMT2AHTTGAA
SCHEMBL1093450 0.72 CNR1 (0.41) CNR1POLBKMT2AMEN1HTT
SCHEMBL24406128 0.71 PTGER4 (0.49) ALDH1A1SMN1; SMN2POLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117956984-A Novel microparticles containing active substances 巴斯夫欧洲公司 2024-04-30 CN disclosed
CN-117794908-A (3-quinolinyl) -quinazolines 巴斯夫欧洲公司 2024-03-29 CN disclosed
CN-117794907-A (3-pyridinyl) -quinazolines 巴斯夫欧洲公司 2024-03-29 CN disclosed