Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267991 | 0.87 | SMN1; SMN2 (0.48) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL2703787 | 0.85 | LMNA (0.42) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL14972966 | 0.83 | LMNA (0.40) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL24583744 | 0.82 | LMNA (0.42) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL26927951 | 0.82 | KDM4E (0.42) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL18131162 | 0.81 | MAPT (0.43) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL26928468 | 0.81 | LMNA (0.45) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL26927791 | 0.80 | LMNA (0.38) | LMNANPC1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL15273679 | 0.80 | LMNA (0.50) | LMNANPC1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20642921 | 0.79 | DGAT1 (0.37) | LMNANPC1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584265-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052690-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |