Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066052 | 1.00 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL27159733 | 1.00 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL28544198 | 1.00 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL29183553 | 1.00 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL21001793 | 1.00 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL805599 | 0.92 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL2749084 | 0.92 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL13422928 | 0.92 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL30828899 | 0.92 | TSHR (0.44) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL12540224 | 0.85 | LMNA (0.41) | TSHRLMNAPPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542523-B | Heterocyclic compounds as PRMT5 inhibitors | 朱比连特埃皮斯科瑞有限责任公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |