Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26646985 | 1.00 | MTOR (0.48) | MTORSMN1; SMN2LMNAMAPK1POLB | |
| SCHEMBL12463160 | 0.86 | SMN1; SMN2 (0.58) | MTORSMN1; SMN2MAPK1POLBALDH1A1 | |
| SCHEMBL20154109 | 0.82 | NPSR1 (0.49) | SMN1; SMN2LMNAMAPK1POLBKDM4E | |
| SCHEMBL26647309 | 0.81 | MTOR (0.46) | MTORSMN1; SMN2LMNAMAPK1POLB | |
| SCHEMBL30068164 | 0.81 | MTOR (0.46) | MTORSMN1; SMN2LMNAMAPK1POLB | |
| SCHEMBL26646837 | 0.80 | CTSK (0.54) | MTORSMN1; SMN2MAPK1POLBKDM4E | |
| SCHEMBL30067892 | 0.80 | CTSK (0.54) | MTORSMN1; SMN2MAPK1POLBKDM4E | |
| SCHEMBL30068009 | 0.80 | PDE10A (0.50) | MTORSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL26646960 | 0.80 | PDE10A (0.50) | MTORSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL26770486 | 0.79 | TGFBR1 (0.39) | MTORALDH1A1NPY5RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |