Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829143 | 1.00 | NOTUM (0.63) | NOTUMSMN1; SMN2HSD17B10CA1CA2 | |
| SCHEMBL3120560 | 0.91 | SMN1; SMN2 (0.74) | NOTUMSMN1; SMN2HSD17B10TSHRMEN1 | |
| SCHEMBL29640094 | 0.91 | SMN1; SMN2 (0.74) | NOTUMSMN1; SMN2HSD17B10TSHRMEN1 | |
| SCHEMBL4865076 | 0.86 | SMN1; SMN2 (0.67) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL29443491 | 0.81 | NOTUM (0.68) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL43169 | 0.81 | NOTUM (0.68) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29858239 | 0.79 | NOTUM (0.66) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5573069 | 0.79 | NOTUM (0.66) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL29510859 | 0.78 | NOTUM (1.00) | NOTUMSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL709869 | 0.78 | NOTUM (1.00) | NOTUMSMN1; SMN2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070274-A | N- (3-fluorophenyl) -6- (6, 7-dimethoxy quinoline-4-oxy) -3, 4-dihydro quinoline-1 (2H) -formamide mesylate crystal form and preparation method thereof | 上海懿峰生物科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-117700358-B | N- (3-fluorophenyl) -6- (6, 7-dimethoxy quinoline-4-oxy) -3, 4-dihydro quinoline-1 (2H) -formamide mesylate crystal form and preparation method thereof | 上海懿峰生物科技有限公司 | 2026-03-17 | — | — | CN | disclosed |
| CN-117700358-A | N- (3-fluorophenyl) -6- (6, 7-dimethoxy quinoline-4-oxy) -3, 4-dihydro quinoline-1 (2H) -formamide mesylate crystal form and preparation method thereof | 上海懿峰生物科技有限公司 | 2024-03-15 | — | — | CN | disclosed |