SCHEMBL30829256

SCHEMBL30829256

Oc1nc2ccccc2nc1OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPT P10636 6/20 0.34
KMT2A Q03164 4/20 0.34
NPSR1 Q6W5P4 3/20 0.34
MEN1 O00255 3/20 0.34
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
GAA P10253 3/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
XBP1 P17861 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 2/20 0.32
NQO2 P16083 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30829254 0.83 KDM4E (0.46) CFTRCYP1A2CYP2C9CYP2C19MAPT
SCHEMBL30829253 0.82 KDM4E (0.53) KDM4E
SCHEMBL30829263 0.82 PABPC1 (0.34) MAPTKMT2ANPSR1MEN1TP53
SCHEMBL30829264 0.82 MAPT (0.37) CFTRCYP1A2MAPTKMT2ANPSR1
SCHEMBL30829250 0.81 MAPT (0.37) CFTRMAPTKMT2ANPSR1MEN1
SCHEMBL30829257 0.81 NQO2 (0.35) MAPTKMT2ANPSR1MEN1GAA
SCHEMBL30829260 0.80 AR (0.33) MAPTKMT2ANPSR1MEN1TP53
SCHEMBL30829261 0.79 MEN1 (0.46) CYP1A2CYP2C9CYP2C19MAPTKMT2A
SCHEMBL30829251 0.79 TDP1 (0.47) CFTRCYP1A2CYP2C9CYP2C19MAPT
SCHEMBL30829255 0.78 CETP (0.38) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117702139-A Method for synthesizing electrocatalytic fluoroalkoxy aryl ether compound 西华师范大学 2024-03-15 CN disclosed