SCHEMBL30829264

SCHEMBL30829264

Oc1nc2cc(Cl)ccc2nc1OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HRH4 Q9H3N8 2/20 0.36
PIK3CG P48736 1/20 0.34
PIK3R1 P27986 1/20 0.33
PIK3CA P42336 1/20 0.33
CFTR P13569 1/20 0.32
NPSR1 Q6W5P4 3/20 0.31
TP53 P04637 2/20 0.31
ALOX15 P16050 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
HIF1A Q16665 1/20 0.31
GMNN O75496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30829260 0.85 AR (0.33) MAPTMEN1KMT2AHRH4NPSR1
SCHEMBL30829254 0.84 KDM4E (0.46) MAPTKDM4EMEN1KMT2ACFTR
SCHEMBL30829253 0.83 KDM4E (0.53) KDM4EDYRK1A
SCHEMBL30829263 0.83 PABPC1 (0.34) MAPTKDM4EMEN1KMT2APIK3R1
SCHEMBL30829256 0.82 CFTR (0.36) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL30829261 0.81 MEN1 (0.46) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL30829255 0.80 CETP (0.38) KDM4EPDK2
SCHEMBL29187237 0.78 KDM4E (0.35) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL29581721 0.74 HSD17B10 (0.53) MAPTKDM4EALDH1A1MEN1KMT2A
SCHEMBL6109697 0.74 HSD17B10 (0.53) MAPTKDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117702139-A Method for synthesizing electrocatalytic fluoroalkoxy aryl ether compound 西华师范大学 2024-03-15 CN disclosed