Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214496 | 1.00 | PTGDR2 (0.44) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20214285 | 0.91 | ALDH1A1 (0.38) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20214519 | 0.87 | ALDH1A1 (0.43) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29579668 | 0.87 | ALDH1A1 (0.43) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20213971 | 0.86 | ALDH1A1 (0.45) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29579216 | 0.86 | ALDH1A1 (0.45) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28343983 | 0.86 | ALDH1A1 (0.41) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20214200 | 0.86 | THRB (0.44) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20214015 | 0.85 | ALDH1A1 (0.44) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29580423 | 0.85 | ALDH1A1 (0.44) | PTGDR2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930533-A | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-110603254-B | Substituted pyrazole compounds and methods of using the same for treating hyperproliferative diseases | 班塔姆制药有限责任公司 | 2024-04-12 | — | — | CN | disclosed |