Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 5/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL30830333 | 0.99 | LIMK1 (0.54) | LIMK1PARP1PDE4APDE4BPDE4C | |
| SCHEMBL5183670 | 0.79 | LIMK1 (0.53) | LIMK1KDM4ECLK1IKBKBCHUK | |
| SCHEMBL5183472 | 0.76 | LIMK1 (0.39) | LIMK1KDM4ECLK1HTTALOX15 | |
| SCHEMBL5776212 | 0.73 | LIMK1 (0.69) | LIMK1PARP1KDM4ECLK1IKBKB | |
| SCHEMBL21813696 | 0.72 | LIMK1 (0.56) | LIMK1PARP1KDM4ECLK1IKBKB | |
| SCHEMBL10507045 | 0.69 | LIMK1 (0.55) | LIMK1KDM4ECLK1ALOX15FTO | |
| SCHEMBL28717624 | 0.66 | LIMK1 (0.47) | LIMK1KDM4ECLK1ALOX15FTO | |
| SCHEMBL8507168 | 0.65 | LIMK1 (0.77) | LIMK1PARP1KDM4ECLK1IKBKB | |
| SCHEMBL22866720 | 0.65 | KDM4E (0.48) | LIMK1KDM4EHTTALOX15HPGD | |
| SCHEMBL29560195 | 0.65 | KDM4E (0.48) | LIMK1KDM4EHTTALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240076301-A1 | Solid Forms of an eIF4E Inhibitor | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2024-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240076301-A1 | Solid Forms of an eIF4E Inhibitor | EIF4E, EIF4EBP1, EIF4A1 | LIMK1 1045/4885PARP1 922/4885PDE4A 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.