Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 20/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831086 | 0.94 | KAT2B (0.41) | KAT2BBRD9 | |
| SCHEMBL30830894 | 0.93 | KAT2B (0.49) | KAT2BBRD9 | |
| SCHEMBL30830912 | 0.91 | KAT2B (0.49) | KAT2BBRD9 | |
| SCHEMBL30830775 | 0.88 | CRBN (0.51) | KAT2BBRD9 | |
| SCHEMBL30831023 | 0.87 | KAT2B (0.55) | KAT2BBRD9 | |
| SCHEMBL30830808 | 0.86 | KAT2B (0.47) | KAT2BBRD9 | |
| SCHEMBL30831090 | 0.85 | KAT2B (0.51) | KAT2BBRD9 | |
| SCHEMBL30830751 | 0.85 | KAT2B (0.55) | KAT2BBRD9 | |
| SCHEMBL30830514 | 0.85 | KAT2B (0.41) | KAT2BBRD9 | |
| SCHEMBL30830813 | 0.85 | KAT2B (0.51) | KAT2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |