Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004299 | 0.87 | HSD17B10 (0.54) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL27950455 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL27314351 | 0.78 | KDM1A (0.50) | ALDH1A1GAAKDM1AMAOAKMT2A | |
| SCHEMBL27314354 | 0.78 | KDM1A (0.50) | ALDH1A1GAAKDM1AMAOAKMT2A | |
| SCHEMBL21221586 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL38657721 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL31091756 | 0.75 | KDM4D (0.45) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL30831046 | 0.75 | KDM4D (0.45) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| Hydrochloric Acid SCHEMBL32677527 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EGAATSHR | |
| SCHEMBL63894 | 0.75 | HDAC3 (0.54) | ALDH1A1HSD17B10KDM4EGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024220843-A1 | TECHNOLOGIES TARGETING CELL STATES | AURON THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |