SCHEMBL308319

SCHEMBL308319

c1ccc(-c2cc3ccccc3[nH]2)nc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.61
KDM4E B2RXH2 6/20 0.59
NPC1 O15118 5/20 0.59
RAB9A P51151 5/20 0.59
LMNA P02545 5/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
HPGD P15428 3/20 0.59
ALDH1A1 P00352 2/20 0.59
AURKA O14965 1/20 0.54
AURKB Q96GD4 1/20 0.54
ITK Q08881 3/20 0.54
CCNB2 O95067 1/20 0.53
CDK1 P06493 1/20 0.53
CCNB1 P14635 1/20 0.53
CDK5 Q00535 1/20 0.53
CDK5R1 Q15078 1/20 0.53
CCNB3 Q8WWL7 1/20 0.53
CYP19A1 P11511 1/20 0.51
METAP1 P53582 3/20 0.50
PKM P14618 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470995 1.00 GSK3B (0.61) GSK3BKDM4ENPC1RAB9ALMNA
Imidazole SCHEMBL27824774 0.87 GSK3B (0.49) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL23641151 0.82 GSK3B (0.62) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL28784366 0.82 ITK (0.57) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL1466825 0.82 SMN1; SMN2 (0.55) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL17548353 0.82 CBFB (0.58) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL694241 0.82 LMNA (0.49) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL2489128 0.81 ITK (0.57) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL30337474 0.81 ITK (0.57) GSK3BKDM4ENPC1RAB9ALMNA
SCHEMBL31626826 0.81 CYP19A1 (0.59) GSK3BKDM4ENPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3710 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624055-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-05-12 US claimed
US-12593378-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-03-31 US claimed
US-12520715-B2 Organic electroluminescent materials and devices UNIVERSITY OF SOUTHERN CALIFORNIA 2026-01-06 US claimed
EP-4633344-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2025-10-15 EP claimed
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US claimed
US-12284911-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-04-22 US claimed
US-20250127032-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-04-17 US claimed
US-20250072274-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-02-27 US claimed
US-20250008761-A1 HEAVY METAL ASSISTED THERMALLY ACTIVATED DELAYED FLUORESCENCE FOR OLEDS THE UNIVERSITY OF SOUTHERN CALIFORNIA 2025-01-02 US claimed
US-20240431205-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-26 US claimed
US-9572815-B2 Methods and compositions of p27KIP1 transcriptional modulators ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2017-02-21 US claimed
US-20160329509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2016-11-10 US claimed
US-9478758-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-10-25 US claimed
US-20160030445-A1 METHODS AND COMPOSITIONS OF P27KIP1 TRANSCRIPTIONAL MODULATORS ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2016-02-04 US claimed
WO-2014145205-A2 METHODS AND COMPOSITIONS OF P27KIP1 TRANSCRIPTION MODULATORS ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2014-09-18 WO claimed
US-8092867-B2 Silicon polymers, methods of polymerizing silicon compounds, and methods of forming thin films from such silicon polymers KOVIO, INC. (US) 2012-01-10 US claimed
US-20090232780-A1 COMPOUNDS THAT ENHANCE ATOH1 EXPRESSION MASSACHUSETTS EYE & EAR INFIRMARY (US) 2009-09-17 US claimed
EP-0080154-B1 N-SUBSTITUTED 2-PYRIDYL INDOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTICAL USE CIBA-GEIGY AG (CH) 1985-08-28 EP claimed
EP-0080154-A2 N-substituted 2-pyridyl indoles, process for their preparation, pharmaceutical compositions containing them, and their therapeutical use CIBA-GEIGY AG (CH) 1983-06-01 EP claimed
EP-0003199-A2 Tetrahydropyridinyl indole derivatives and their salts, process for their preparation, their use as medicines and pharmaceutical compositions containing them ROUSSEL-UCLAF (FR) 1979-07-25 EP claimed