Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838565 | 0.79 | CCR2 (0.37) | NR3C1PGRNR3C2ARCCR8 | |
| SCHEMBL5271973 | 0.74 | TDP1 (0.43) | PARP1RECQLTDP1BTKCCR8 | |
| SCHEMBL2983820 | 0.71 | ALDH1A1 (0.38) | PARP1RECQLTDP1BTKCCR8 | |
| SCHEMBL31603821 | 0.69 | TTR (0.50) | L3MBTL1TDP1KMT2A | |
| SCHEMBL11528163 | 0.69 | TTR (0.50) | L3MBTL1TDP1KMT2A | |
| SCHEMBL29212439 | 0.69 | CA12 (0.37) | NR3C1PGRNR3C2ARBRD4 | |
| SCHEMBL3068349 | 0.67 | AHR (0.42) | L3MBTL1PARP1RECQLTDP1BTK | |
| SCHEMBL15826681 | 0.67 | AXL (0.39) | NR3C1PGRPARP1RECQLTDP1 | |
| SCHEMBL31488003 | 0.67 | AHR (0.42) | L3MBTL1PARP1RECQLTDP1BTK | |
| SCHEMBL3061065 | 0.67 | IDO1 (0.50) | NR3C1PGRTDP1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968361-A | Compounds targeting p 53Y 220 mutants | 北京加科思新药研发有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |