Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378528 | 0.86 | GPR119 (0.49) | GPR119CKS1BSKP1SKP2SMARCA2 | |
| SCHEMBL26113732 | 0.85 | POLB (0.49) | GPR119CKS1BSKP1SKP2SMARCA2 | |
| SCHEMBL28495254 | 0.84 | GPR119 (0.47) | GPR119CKS1BSKP1SKP2MAPT | |
| SCHEMBL31651742 | 0.84 | GPR119 (0.47) | GPR119CKS1BSKP1SKP2SMARCA2 | |
| SCHEMBL24989545 | 0.82 | GPR119 (0.47) | GPR119CKS1BSKP1SKP2SMARCA2 | |
| SCHEMBL2420435 | 0.81 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2MAPT | |
| SCHEMBL30893588 | 0.81 | GPR119 (0.52) | GPR119CKS1BSKP1SKP2MAPT | |
| SCHEMBL5467171 | 0.80 | GPR119 (0.65) | GPR119CKS1BSKP1SKP2MAPT | |
| SCHEMBL30833113 | 0.78 | PIK3CA (0.49) | GPR119CKS1BSKP1SKP2SMARCA2 | |
| SCHEMBL31651718 | 0.78 | TLR9 (0.50) | GPR119CKS1BSKP1SKP2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |