Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833112 | 0.92 | PIK3CA (0.48) | PIK3CASMN1; SMN2USP2GPR119SMARCA2 | |
| SCHEMBL31046207 | 0.80 | GPR119 (0.41) | GPR119 | |
| SCHEMBL29335912 | 0.80 | GPR119 (0.41) | GPR119 | |
| SCHEMBL31378528 | 0.79 | GPR119 (0.49) | SMN1; SMN2GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL26113732 | 0.78 | POLB (0.49) | SMN1; SMN2GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL30833118 | 0.78 | GPR119 (0.48) | SMN1; SMN2GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL24989545 | 0.78 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL31651742 | 0.78 | GPR119 (0.47) | SMN1; SMN2GPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL30833091 | 0.76 | PIK3CA (0.40) | PIK3CAALDH1A1 | |
| SCHEMBL30833145 | 0.76 | CKS1B (0.42) | PIK3CASMN1; SMN2USP2GPR119SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587432-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | Cerevel Therapeutics, LLC (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059249-A1 | M4 ACTIVATORS/MODULATORS AND USES THEREOF | CEREVEL THERAPEUTICS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |