Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195125 | 1.00 | MAPT (0.42) | MAPTNPC1RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL28046868 | 0.87 | ALDH1A1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8967901 | 0.80 | ALDH1A1 (0.52) | MAPTNPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL29805068 | 0.80 | ALDH1A1 (0.52) | MAPTNPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL29195122 | 0.77 | CYP19A1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL8405748 | 0.73 | ALDH1A1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1401807 | 0.71 | ALDH1A1 (0.48) | MAPTCYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL188386 | 0.71 | ALDH1A1 (0.48) | MAPTCYP19A1ALDH1A1MEN1KMT2A | |
| SCHEMBL31275823 | 0.71 | ALDH1A1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15508187 | 0.70 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677613-A | Process for producing synthetic intermediate of monocyclic pyridine derivative | 卫材R&D管理有限公司 | 2024-03-08 | — | — | CN | disclosed |