Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15952462 | 1.00 | BACE1 (0.41) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL15951984 | 0.92 | BACE1 (0.41) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL15952629 | 0.85 | NCF1 (0.38) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL9735678 | 0.84 | MEN1 (0.40) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL15953327 | 0.84 | PTK6 (0.45) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL9736720 | 0.82 | SMPD1 (0.46) | MEN1KMT2ATYRMAPTTLR8 | |
| SCHEMBL1959555 | 0.82 | POLB (0.50) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL15952457 | 0.81 | GPR84 (0.41) | BACE1MEN1POLBMAPK1KMT2A | |
| SCHEMBL9735907 | 0.80 | SMPD1 (0.44) | MEN1KMT2AMAPTTLR8GPR84 | |
| SCHEMBL8052978 | 0.78 | MEN1 (0.40) | BACE1MEN1POLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677613-A | Process for producing synthetic intermediate of monocyclic pyridine derivative | 卫材R&D管理有限公司 | 2024-03-08 | — | — | CN | disclosed |