Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25219373 | 1.00 | PRMT5 (0.35) | PRMT5WDR77LMNAHTTNPSR1 | |
| SCHEMBL23087512 | 0.85 | ADORA1 (0.44) | PRMT5WDR77LMNAADORA1PDE1A | |
| SCHEMBL31496951 | 0.85 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL23087315 | 0.84 | AR (0.41) | PRMT5WDR77LMNAHTTNPSR1 | |
| SCHEMBL23087286 | 0.82 | ADORA1 (0.39) | PRMT5WDR77LMNAHTTNPSR1 | |
| SCHEMBL30833185 | 0.82 | POLB (0.50) | PRMT5WDR77ARADORA1PDE1A | |
| SCHEMBL25223292 | 0.82 | POLB (0.50) | PRMT5WDR77ARADORA1PDE1A | |
| SCHEMBL29915079 | 0.79 | PRMT5 (0.35) | PRMT5WDR77LMNAHTTNPSR1 | |
| SCHEMBL27002284 | 0.79 | PRMT5 (0.35) | PRMT5WDR77LMNAHTTNPSR1 | |
| SCHEMBL30970711 | 0.77 | ADORA1 (0.38) | PRMT5WDR77LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-117730075-A | Pyrazole derivative, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |