Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776676 | 0.95 | CDK1 (0.48) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL30776675 | 0.95 | CDK1 (0.48) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL27088124 | 0.86 | MMP13 (0.47) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL30779339 | 0.86 | MMP13 (0.47) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL30815988 | 0.84 | MMP13 (0.47) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL26976050 | 0.84 | MMP13 (0.47) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL31195312 | 0.84 | MMP13 (0.48) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL30751748 | 0.81 | MMP13 (0.48) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL3598543 | 0.77 | MMP13 (0.54) | MMP13CDK1CCNB1MMP2MMP14 | |
| SCHEMBL30910162 | 0.75 | KDM4E (0.43) | MMP13KDM5AKDM5BRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180209-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-12-31 | — | — | US | disclosed |
| US-12173003-B1 | Pyrrolo[3,2-C][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-12-24 | — | — | US | disclosed |
| US-11945820-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | King Faisal University (SA) | 2024-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12173003-B1 | Pyrrolo[3,2-C][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A2, CSNK2A3, CKS2 | MMP13 3728/4885CDK1 30/4885CCNB1 260/4885 |
| US-11945820-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A2, CSNK2A3, CKS2 | MMP13 3728/4885CDK1 30/4885CCNB1 260/4885 |
| US-12180209-B1 | Pyrrolo[3,2-c][2,6]naphthyridine-2-carboxylic acid compounds as CK2 inhibitors | CSNK2A2, CSNK2A3, CKS2 | MMP13 3728/4885CDK1 30/4885CCNB1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.