Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180955 | 0.85 | BCHE (0.50) | HRH3MEN1KMT2A | |
| SCHEMBL27777168 | 0.81 | SRD5A2 (0.56) | MAPTPIK3CGADORA3 | |
| SCHEMBL5746976 | 0.80 | TDP1 (0.54) | HRH3CYP2D6CYP2C19KDM4E | |
| SCHEMBL30833298 | 0.79 | HTR1A (0.50) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL5748842 | 0.79 | TDP1 (0.58) | HRH3CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL5746589 | 0.79 | TSHR (0.55) | HRH3CYP2D6CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL5745224 | 0.78 | HRH3 (0.57) | HRH3CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL5747298 | 0.77 | TDP1 (0.50) | HRH3CYP2D6CYP2C19KDM4E | |
| SCHEMBL5746509 | 0.76 | TDP1 (0.54) | HRH3CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL29180947 | 0.76 | HRH3 (0.45) | HRH3ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800898-A | Carbazole compound and application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |