Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 7/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777168 | 0.79 | SRD5A2 (0.56) | HTR1APIK3CGADORA3LTA4HSRD5A2 | |
| SCHEMBL30833303 | 0.79 | HRH3 (0.48) | PIK3CGADORA3MEN1MAPTKMT2A | |
| SCHEMBL30833301 | 0.72 | PARP1 (0.58) | ADORA3SRD5A2MAPTKDM4EALDH1A1 | |
| SCHEMBL28336625 | 0.71 | HTR6 (0.58) | HTR1AHTR6HTR3EHTR3BADRB1 | |
| SCHEMBL335477 | 0.70 | LTA4H (0.64) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL29180957 | 0.70 | HTR1A (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL2156238 | 0.69 | LTA4H (0.62) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL5018077 | 0.68 | KIF11 (0.53) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL5747298 | 0.68 | TDP1 (0.50) | HTR6LTA4HKDM4EHSD17B10TDP1 | |
| SCHEMBL5746976 | 0.68 | TDP1 (0.54) | HTR6LTA4HKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800898-A | Carbazole compound and application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |