Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | WNT3 | P56703 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833449 | 0.92 | RORC (0.42) | MEN1KMT2ATSHRRORCALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30833404 | 0.91 | RORC (0.40) | MEN1KMT2ATSHRRORCALDH1A1 | |
| SCHEMBL17942446 | 0.83 | TSHR (0.52) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL30833387 | 0.82 | ABCC9 (0.41) | MEN1KMT2ATSHRALDH1A1USP2 | |
| SCHEMBL17949198 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL17949199 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL17949166 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL30833428 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL29529870 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 | |
| SCHEMBL29529953 | 0.80 | TSHR (0.48) | KMT2ATSHRRORCALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |