Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | WNT3 | P56703 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833472 | 1.00 | HTR6 (0.47) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL17949307 | 1.00 | HTR6 (0.47) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL30833407 | 1.00 | HTR6 (0.47) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL17949306 | 1.00 | HTR6 (0.47) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL17948971 | 1.00 | HTR6 (0.47) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL17942305 | 0.90 | HTR6 (0.50) | HTR6HTR2CHTR2BNR1I2CYP3A4 | |
| SCHEMBL18025937 | 0.86 | HTR6 (0.46) | HTR6HTR2CNR1I2CYP3A4CACNA1B | |
| SCHEMBL17942386 | 0.86 | HTR2C (0.47) | HTR6HTR2CHTR2BWNT3SFRP1 | |
| SCHEMBL30833452 | 0.86 | HTR2C (0.47) | HTR6HTR2CHTR2BWNT3SFRP1 | |
| SCHEMBL18027382 | 0.83 | HTR2A (0.56) | HTR6HTR2CNR1I2CYP3A4CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |