Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 17/20 | 0.46 |
| ▸ | WNT3 | P56703 | 1/20 | 0.39 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942386 | 1.00 | HTR2C (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL17942305 | 0.87 | HTR6 (0.50) | HTR2CHTR2BHTR6 | |
| SCHEMBL17949307 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL30833392 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL17948971 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL30833472 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL30833407 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL17949306 | 0.86 | HTR6 (0.47) | HTR2CHTR2BHTR6WNT3SFRP1 | |
| SCHEMBL17942395 | 0.78 | CYP3A4 (0.48) | HTR2C | |
| SCHEMBL22585222 | 0.77 | F10 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |