Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | WNT3 | P56703 | 1/20 | 0.32 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833421 | 0.90 | RORC (0.36) | RORCEPHX2MAPTALDH1A1PRMT5 | |
| SCHEMBL17942465 | 0.83 | TRPV1 (0.39) | RORCEPHX2MAPTTSHRLMNA | |
| SCHEMBL30833427 | 0.83 | RORC (0.36) | RORCEPHX2MAPTALDH1A1PRMT5 | |
| SCHEMBL30833456 | 0.82 | RORC (0.35) | RORCEPHX2MAPTALDH1A1PRMT5 | |
| SCHEMBL19996410 | 0.79 | TRPV1 (0.38) | RORCEPHX2LMNATRPV1 | |
| SCHEMBL30833449 | 0.79 | RORC (0.42) | RORCEPHX2MAPTALDH1A1HPGD | |
| SCHEMBL30833471 | 0.77 | RORC (0.36) | RORCEPHX2MAPTALDH1A1HPGD | |
| SCHEMBL17949080 | 0.77 | EPHX2 (0.38) | EPHX2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL29529743 | 0.77 | EPHX2 (0.38) | EPHX2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL30833492 | 0.77 | RORC (0.36) | RORCEPHX2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |