Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | WNT3 | P56703 | 1/20 | 0.32 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833427 | 0.89 | RORC (0.36) | RORCEPHX2MAPTWNT3SFRP1 | |
| SCHEMBL17949310 | 0.84 | SPR (0.36) | RORCEPHX2SCN10ALMNATRPV1 | |
| SCHEMBL30833437 | 0.82 | RORC (0.37) | RORCEPHX2MAPTWNT3SFRP1 | |
| SCHEMBL30833421 | 0.80 | RORC (0.36) | RORCEPHX2MAPTWNT3SFRP1 | |
| SCHEMBL17948928 | 0.80 | LMNA (0.35) | RORCEPHX2ALDH1A1TSHRLMNA | |
| SCHEMBL19996409 | 0.79 | SPR (0.35) | RORCEPHX2SCN10ALMNATRPV1 | |
| SCHEMBL30833399 | 0.79 | MEN1 (0.38) | WNT3SFRP1ALDH1A1LMNATRPV1 | |
| SCHEMBL30833432 | 0.77 | EPHX2 (0.37) | RORCEPHX2WNT3SFRP1ALDH1A1 | |
| SCHEMBL30833471 | 0.76 | RORC (0.36) | RORCEPHX2MAPTWNT3SFRP1 | |
| Trifluoroacetic Acid SCHEMBL30833404 | 0.76 | RORC (0.40) | RORCEPHX2MAPTWNT3SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |