Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942403 | 1.00 | CYP3A4 (0.45) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17948943 | 0.84 | TSHR (0.47) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL29530688 | 0.84 | TSHR (0.47) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL30833388 | 0.83 | RIPK1 (0.38) | CYP3A4CACNA1BNR1I2SCD5KMT2A | |
| SCHEMBL17949487 | 0.83 | FAAH (0.50) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17949198 | 0.83 | TSHR (0.48) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17948950 | 0.83 | NPC1 (0.47) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17949199 | 0.83 | TSHR (0.48) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17949176 | 0.83 | NR1I2 (0.44) | CYP3A4CACNA1BNR1I2TSHRNPC1 | |
| SCHEMBL17948942 | 0.83 | NR1I2 (0.44) | CYP3A4CACNA1BNR1I2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |