Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942485 | 1.00 | NAMPT (0.37) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL30833448 | 0.86 | NAMPT (0.37) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL17942410 | 0.86 | NAMPT (0.37) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL17942341 | 0.85 | KDM4E (0.38) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL29529392 | 0.84 | CA12 (0.39) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL17949343 | 0.84 | CA12 (0.39) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL17948889 | 0.84 | ELOVL6 (0.43) | KDM4EALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL30833492 | 0.83 | RORC (0.36) | NAMPTTRPV1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL17949147 | 0.82 | NPY5R (0.39) | NAMPTTRPV1KDM4EGAAALDH1A1 | |
| SCHEMBL29529835 | 0.82 | NPY5R (0.39) | NAMPTTRPV1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |