SCHEMBL30833582

SCHEMBL30833582

O=C1c2ccccc2C2(c3ccccc31)c1ccccc1-c1ccc[13cH]c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 1/20 0.55
KCNQ2 O43526 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
S100A4 P26447 2/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
OPRK1 P41145 1/20 0.46
THRB P10828 2/20 0.46
MAOA P21397 2/20 0.46
APAF1 O14727 2/20 0.46
TDP2 O95551 2/20 0.46
CES2 O00748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30501016 1.00 MEN1 (0.55) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL357510 1.00 MEN1 (0.55) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL29355276 0.86 KMT2A (0.56) MEN1KMT2ACDC25BS100A4KDM4E
SCHEMBL44942 0.86 KMT2A (0.56) MEN1KMT2ACDC25BS100A4KDM4E
SCHEMBL17629222 0.84 LMNA (0.50) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL8930207 0.84 MCL1 (0.48) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL29598404 0.84 LMNA (0.50) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL30805724 0.83 MEN1 (0.52) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL14190761 0.83 MEN1 (0.52) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL18374553 0.83 KMT2A (0.54) MEN1KMT2ACDC25BS100A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462579-B Preparation method of spirofluorene anthrone compound 大连理工大学 2024-04-05 CN disclosed