SCHEMBL357510

SCHEMBL357510

O=C1c2ccccc2C2(c3ccccc31)c1ccccc1-c1ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 1/20 0.55
KCNQ2 O43526 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
S100A4 P26447 2/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
OPRK1 P41145 1/20 0.46
THRB P10828 2/20 0.46
MAOA P21397 2/20 0.46
APAF1 O14727 2/20 0.46
TDP2 O95551 2/20 0.46
CES2 O00748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30501016 1.00 MEN1 (0.55) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL30833582 1.00 MEN1 (0.55) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL29355276 0.86 KMT2A (0.56) MEN1KMT2ACDC25BS100A4KDM4E
SCHEMBL44942 0.86 KMT2A (0.56) MEN1KMT2ACDC25BS100A4KDM4E
SCHEMBL17629222 0.84 LMNA (0.50) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL8930207 0.84 MCL1 (0.48) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL29598404 0.84 LMNA (0.50) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL30805724 0.83 MEN1 (0.52) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL14190761 0.83 MEN1 (0.52) MEN1KMT2ACDC25BKCNQ2CYP1A2
SCHEMBL18374553 0.83 KMT2A (0.54) MEN1KMT2ACDC25BS100A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130105786-A1 NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-05-02 US claimed
CN-111511733-B Compound and organic light emitting device comprising the same 株式会社LG化学 2023-09-15 CN disclosed
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-05-11 US disclosed
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed
CN-108138041-B Double spiro-type compound and organic light emitting diode comprising the same 株式会社LG化学 2020-06-05 CN disclosed
CN-107250101-B Double spiro-type compound and organic light emitting device comprising the same 株式会社LG化学 2020-03-31 CN disclosed
EP-3345982-B1 DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2020-03-18 EP disclosed
US-20190345082-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2019-11-14 US disclosed
US-20130105786-A1 NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-05-02 US disclosed
US-20130105786-A1 NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-05-02 US disclosed
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-23 US disclosed
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-08-23 US disclosed
WO-2012008557-A1 NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-01-19 WO disclosed
WO-2012008557-A1 NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-01-19 WO disclosed
EP-2365735-A2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES INC. (JP) 2011-09-14 EP disclosed
WO-2011050888-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
US-7318966-B2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2008-01-15 US disclosed
US-7318966-B2 Luminescent element material and luminescent element comprising the same TORAY INDUSTRIES, INC. (JP) 2008-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 MEN1 1825/4885KMT2A 719/4885CDC25B 1149/4885
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same NR2E3, CRY1, CRY2 MEN1 1575/4885KMT2A 942/4885CDC25B 1340/4885
US-20120211701-A1 MATERIALS FOR ELECTRONIC DEVICES XPOT, ETV6, ERCC1 MEN1 29/4885KMT2A 2206/4885CDC25B 2518/4885
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same DCX, TERT, TELO2 MEN1 2052/4885KMT2A 884/4885CDC25B 217/4885
US-20190345082-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME NR2E3, CRY1, CRY2 MEN1 1575/4885KMT2A 942/4885CDC25B 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.