Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833622 | 0.96 | OPRM1 (0.66) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL31412199 | 0.96 | OPRM1 (0.66) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL29702054 | 0.96 | OPRM1 (0.66) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL30833607 | 0.95 | SLC6A2 (0.65) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL29576785 | 0.95 | SLC6A2 (0.74) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL31519794 | 0.94 | SLC6A2 (0.70) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL29351169 | 0.91 | OPRM1 (0.67) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL30423227 | 0.91 | OPRM1 (0.74) | OPRM1OPRD1SLC6A2 | |
| SCHEMBL29571797 | 0.91 | OPRM1 (0.74) | OPRM1OPRD1SLC6A2 | |
| SCHEMBL30957420 | 0.90 | OPRM1 (0.61) | OPRM1OPRD1OPRK1SLC6A2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109936-A1 | NOVEL MACROCYCLIC OPIOID PEPTIDES | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885OPRD1 5/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.