Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | ULK1 | O75385 | 2/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833652 | 0.84 | IGF1R (0.40) | ALKZAP70CDK19MEN1KMT2A | |
| SCHEMBL30833707 | 0.81 | ALK (0.40) | EGFRULK1ALKZAP70CDK19 | |
| SCHEMBL2843128 | 0.79 | ALK (0.58) | EGFRULK1ALKZAP70CDK19 | |
| SCHEMBL30833796 | 0.79 | IGF1R (0.46) | EGFRALKZAP70CDK19MEN1 | |
| SCHEMBL29190684 | 0.79 | EGFR (0.45) | EGFRULK1ALKZAP70CDK19 | |
| SCHEMBL29190532 | 0.77 | EGFR (0.45) | EGFRULK1ALKZAP70CDK19 | |
| SCHEMBL31204509 | 0.76 | MEN1 (0.38) | EGFRALKCDK19MEN1KMT2A | |
| SCHEMBL375527 | 0.74 | IGF1R (0.50) | ULK1ALKZAP70MEN1KMT2A | |
| SCHEMBL29190528 | 0.73 | IGF1R (0.43) | EGFRULK1ALKZAP70CDK19 | |
| SCHEMBL38657160 | 0.71 | MEN1 (0.48) | EGFRULK1ALKZAP70CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |