Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | IGF1R | P08069 | 4/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833726 | 0.84 | IGF1R (0.40) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL30833675 | 0.81 | EGFR (0.42) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL2843128 | 0.79 | ALK (0.58) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL30833628 | 0.79 | IGF1R (0.46) | ALKCDK19KMT2AMEN1IGF1R | |
| SCHEMBL29190684 | 0.77 | EGFR (0.45) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL29190532 | 0.74 | EGFR (0.45) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL29190528 | 0.71 | IGF1R (0.43) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL25056307 | 0.70 | MEN1 (0.52) | ALKCDK19KMT2AMEN1IGF1R | |
| SCHEMBL29190641 | 0.69 | IGF1R (0.51) | ALKCDK19KMT2AMEN1EGFR | |
| SCHEMBL6213223 | 0.69 | ATM (0.54) | KMT2AMEN1EGFRIGF1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |