Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833643 | 0.88 | ALK (0.43) | MAPK8MAPK9MAPK10ALKCDK7 | |
| SCHEMBL30833659 | 0.85 | AURKA (0.48) | KMT2AMAPK8ALKCDK7CDK9 | |
| SCHEMBL30833733 | 0.85 | PIN1 (0.36) | MEN1KMT2AALKCDK7CDK9 | |
| SCHEMBL30833765 | 0.85 | PKMYT1 (0.38) | IGF1RMEN1KMT2AALKCDK7 | |
| SCHEMBL25056307 | 0.83 | MEN1 (0.52) | IGF1RMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL30833703 | 0.82 | TRPV1 (0.47) | IGF1RCDK7CDK9AURKBTRPV1 | |
| SCHEMBL375527 | 0.82 | IGF1R (0.50) | IGF1RMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL30833652 | 0.81 | IGF1R (0.40) | IGF1RMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL17544600 | 0.81 | IGF1R (0.51) | IGF1RMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL30088390 | 0.81 | IGF1R (0.51) | IGF1RMEN1KMT2AMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |